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Published on Apr 17, 2021
Solve the vignette
Solve the vignette

Since we have got time we shall break it and learn.  Now look at the below question.  Read the entire question fast without any bias. Each and every word. 


A 17- year old male presents with a spontaneous hematoma on the dorsum of the right foot. He says that it started as a bruise without any history of preceding trauma, then it gradually increased to the size of a tennis ball. Detailed medical history revealed that about a year before the development of the hematoma, he also started noticing easy bruising with minor trauma. He also reported lethargy and palpitations. On physical examination, the patient was well oriented, alert, and conscious. The swelling was warm and tender to touch, and the size of hematoma is about 5x5 cm with approximately 1.5 cm depth. Examination of all the other systems did not reveal any significant findings. Blood workup showed a platelet count of 250,000 platelets/microliter, prothrombin time of 12 seconds, activated partial thromboplastin time of 62 seconds and bleeding time of 10 minutes. Coagulation factor assays will most likely demonstrate autoantibodies towards which one of the following?


Now let's look what you should have grabbed while reading them. !?

A 17- year old male presents with a spontaneous hematoma on the dorsum of the right foot. He says that it started as a bruise without any history of preceding trauma, then it gradually increased to the size of a tennis ball. Detailed medical history revealed that about a year before the development of the hematoma, he also started noticing easy bruising with minor trauma. He also reported lethargy and palpitations. On physical examination, the patient was well oriented, alert, and conscious. The swelling was warm and tender to touch, and the size of hematoma is about 5x5 cm with approximately 1.5 cm depth. Examination of all the other systems did not reveal any significant findings. Blood workup showed a platelet count of 250,000 platelets/microliter, prothrombin time of 12 seconds, activated partial thromboplastin time of 62 seconds and bleeding time of 10 minutes. Coagulation factor assays will most likely demonstrate autoantibodies towards which one of the following?

The salient points 

  • Joint Hematoma 
  • With past medical history
  • Elevated aPTT - Rest normal 


Now the question is very simple with important data points. The answer is ??