Which of the following proteins does HPV vaccine target?

a.     E6, E7

b.     E1 E2

c.     L1

d.     L2

Answer is L1.  
Explanation  

The vaccines target HPV L1 major capsid protein, which can assemble to form virus-like particles (VLPs) morphologically resembling native virions, to generate robust antibody responses and prevent HPV infection.

• Gardasil contains VLPs for HPV-16 and -18, associated with cervical cancer, and VLPs for HPV-6 and -11, associated with benign genital warts.
• Cervarix contains only HPV-16 and -18 VLPs.

Make the best use of the last month. Revise Pathology - Subscribe here today (Valid till may INICET - with more questions based on INICET pattern post NEET). 3rd round of revision focussed on NEET PG will be starting in few days.