A 36-year-old male is evaluated for the fatigue of 3 months duration. He admits to easy bruising, rash over his lower extremities, and frequent respiratory infections. He had rheumatoid arthritis, schizophrenia, and history of Rocky Mountain Spotted Fever when he was 5 years old requiring antibiotics. Medications are chlorpromazine and gold. He works at a paint manufacturing company. Temperature is 38°C (100.4°F), blood pressure is 100/58 mmHg, pulse rate is 94/min and regular, respiratory rate is 17/min, and oxygen saturation is 92% on ambient air. Physical examination reveals a gentleman in no acute distress. There is conjunctival pallor and mild oozing of blood at gingival mucosa. There are rales in the left lower lung field. The stool is guaiac negative. Petechiae is present over bilateral lower extremities. Chest x-ray demonstrates consolidation in the left lower lung. Results of laboratory studies are notable for hemoglobin 5.5 g/dL, platelets 50000, and white blood cell count 1000 with 30% neutrophils. The peripheral smear is negative for blasts or schistocytes. Bone marrow biopsy demonstrates the paucity of cells with fat infiltration. Which of the following symptoms are not characteristic of this patient's most likely disease?

1.Bruising, purpura, bleeding - thrombocytopenia
2.Fatigue, shortness of breath - anemia
3.Fatigue - leukopenia
4.Infection - leukopenia

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