Last question answer - Ghrelin 

A 63-year-old woman presents to her physician with polyuria and polydipsia. On physical exam, she appears to have scattered dot/blot hemorrhages and hard exudates in the periphery of her left eye; maculae are intact bilaterally. The fasting glucose level is 170 mg/dl. She was diagnosed with type 2 diabetes mellitus (T2DM). Which of the following most likely occurs in the early stages of type 2 diabetes?

1.Increased insulin sensitivity
2.Decreased insulin sensitivity
3.High circulating levels of C-peptide
4.Low circulating levels of C-peptide

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