Which of the following immunostains can aid in the differentiation between a reactive mesothelial cells and mesothelioma?
ANswer is BAP 1 - Below is an extremely important table for Lung Tumours
Mesothelioma | Reactive mesothelial cells | |
BAP1 | Lost (60% of cases) | Retained |
MTAP | Lost | Retained |
EMA (E29 clone) | Strong membranous | Cytoplasmic / weak membranous |
Desmin | Negative | Positive |
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