Published on Oct 12, 2020
Robbins Review Vignettes

An experiment introduces a “knockout” gene mutation into a cell line. The frequency of cell karyorrhexis and cytoplasmic fragmentation is increased, compared with a cell line without the mutation. Overall survival of the mutant cell line is reduced. Which of the following genes is most likely to be affected by this mutation?

  • BAX
  • BCL-2
  • C-MYC
  • FAS


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