Published on Oct 14, 2020
Robbins Review Vignettes

A 30-year-old man comes to his physician because he has noticed increasing enlargement and a feeling of heaviness in his scrotum for the past year. On physical examination, the right testis is twice its normal size, and it is firm and slightly tender. An ultrasound examination shows a 3.5-cm solid mass in the right testis. An abdominal CT scan shows enlargement of the para-aortic lymph nodes. Multiple lung nodules are seen on a chest radiograph. Laboratory findings include markedly increased serum levels of chorionic gonadotropin and α-fetoprotein. Which of the following testicular neoplasms is the most likely diagnosis?

  • Leydig cell tumor
  • Mixed germ cell tumor
  • Pure spermatocytic seminoma
  • Choriocarcinoma


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