• Agenesis -  Absent organ due to absent primordial tissue.
• Aplasia - Absent organ despite presence of primordial tissue. 
• Hypoplasia -  Incomplete organ development; primordial tissue present. 
• Disruption -  2° breakdown of previously normal tissue or structure (eg, amniotic band syndrome). 
• Deformation - Extrinsic disruption (eg, multiple gestations - crowding - foot deformities); occurs after embryonic period. 

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