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Robbins Review Vignettes

In a clinical trial, a chemotherapeutic agent is given to patients with breast cancer metastases. Samples of the cancer cells are obtained and assessed for the presence of death of tumor cells by apoptosis. Mutational inactivation of which of the following products is most likely to render tumor cells resistant to the effects of such an agent? □ (A) BCL-2 □ (B) p53 □ (C) NF-κB □ (D) Cytochrome P-450 Let's learn conceptually..  - Subscribe here today and gain access to conceptual classes in Pathology for your upcoming NEET exams.. #pathocub

Flask Shaped Ulcer

Flask shaped ulcer in Amoebic Colitis.Flask shaped ulcer is a microscopic finding seen in amoebic colitis The base of the ulcer rests on Muscularis PropriaRevise conceptually in the left days towards your NEET - Get your scheduled videos + 600+ clinical vignettes spanning all systems - Subscribe here today

Robbins Review Vignettes

After the birth of her first child, a 23-year-old woman breastfed the infant for about 1 year. Which of the following processes that occurred in the breast during pregnancy allowed her to breastfeed the infant? □ (A) Stromal hypertrophy □ (B) Lobular hyperplasia □ (C) Epithelial dysplasia □ (D) Intracellular accumulation of fat Let's learn conceptually. And put an end to procrastination this new year !  - Subscribe here today and gain access to conceptual classes in Pathology for your upcoming NEET exams.. #pathocub

A happy new year !

It was a roller coster ride, last year isn't ?2020 was no ordinary year, it was special. You must be wondering what special, its special in every aspect !! It taught us what boredom is...It taught us how to survive with limited resources...It taught us what is must and what is not...It taught to us what really matters to us... Above all it taught us how to survive all this and come out victorious - It taught us the most important goals in our live. And now we enter to 2021 - actually it should be 2020-won (2021)  You cannot ask for a better teacher. Let's all rejoice and leave the sad things and baggages back in 2020 and lets start the fresh day with loads of happiness and positivity ! We have won over 20-20 itself ! We shall survive anything and everything :) Wish you all a very happy new yeear...

Robbins Review Vignettes

Last question answer - Hairy cellA 40-year-old chronic alcoholic with no other medical history died after an alcohol-related seizure, in which he fell down the stairs at his house and fractured his neck. An autopsy is performed that reveals a diffusely golden-yellow discolored liver. Microscopic examination of the liver reveals almost every hepatocyte to be filled with one large vacuole or a few smaller vacuoles. Which of the following mechanisms most likely caused this intracellular inclusion?  Abnormal metabolismA defect in protein foldingThe lack of an enzyme Ingestion of indigestible material Stop Procrastination and start watching Scheduled lectures daily and tests after every lecture and regularise your study pattern - Subscribe here today to give your best for upcoming NEET PG

Robbins Review Vignettes

A 65-year-old male with a past medical history of hypertension and hyperlipidemia presents to the hospital complaining of fatigue and abdominal fullness. He states that he had a recent dental procedure with persistent gingival bleeding, but he did not think much of it at the time. On physical examination, he is found to have splenomegaly. His examination reveals a temperature of 98.8 F (37.1 C), a blood pressure of 100/62 mmHg, a heart rate of 92 beats/min, and a respiratory rate of 18/min. Laboratory workup shows an elevated acid phosphatase that, when oxidized, turned into purple color. Which of the following cells would characteristically be seen in his blood smear?1.Hairy cells2.Smudge cells3.Myeloblasts with Auer rods4.Reed-Sternberg cellsRevision series -  Stop Procrastination and Scheduled lectures and tests after every lecture - Subscribe here today to give your best for upcoming NEET PG

What you would have done ?

I have always wanted to have a basic understanding of economy and people management classes to be included into the medical curriculum, have written to MCI, but of now use, shall be writing to NMC as well. Because when you freshly graduate with and lets say with top most marks in your university and go to job - we are expected to know about the economy and people management. Economy you will in due course, but people management is a skill. Personally had struggled a lot to balance between things and have made quite a few worst decisions in life in relation to lab and people management and have burnt the finger badly. So i would love if i can give you heads up on few scenarios worth while which comes in day to day life. Afterall it's a skill, you guys will master it once you get exposed, so learn from my mistakes :) This was a real life incident which happened A lab kit of CA19-9 went missing yesterday from our lab. (worth Rs.15,000).  The last test done was on 23rd of november. And when searched for yesterdays case to process the kit went missing. All the technicians had got the rotation in the past 5 days - Totally we have 7 technical staffs. Now I am in a position to rectify this. I shall tell my problems and you decide and think how to handle the situation. 1) Management should know this. So there should be a replacement of the money. To take it from 7 technical staff for one persons mistake would be bad2) There was a newly joined technical staff - 3 weeks back. Would I doubt that person .? Since this is the first time happening in the lab -  naturally the doubt will shift to the new person. How do I make the person comfortable and convey that you are not only the point of focus. I dont want any of the employee be dejected and feel cornered3) This incident should not repeat, what all should I do for that ?4) If you find out the person who took it by some means, what action you would take on the person.? So for a change we shall start our morning by giving some food to our brain. You are the boss here, you need not tell me. But think for yourself what will you do. !? A Very Good Morning. !

PAP - EM image

There have been quite a few EM images asked in your exams. Let's see them one by one - Image source Robbins. Lets learn Pathology Conceptually - Subscribe here today - Better late than never. If you have been lethargic waiting for the push to make your schedule streamlined -  Be a part of #pathocubsPulmonary alveolar proteinosis associated with mutation of the ABCA3 gene.An electron micrograph shows type 2 pneumocytes containing small surfactant lamellae with electron dense cores, an appearance that is characteristic of cases associated with ABCA3 mutations. 

Airway Remodelling

Airway remodelling in AsthmaThickening of airway wallSub–basement membrane fibrosis (due to deposition of type I and III collagens)Increased vascularity Increase in the size of the submucosal glands and number of airway goblet cellsHypertrophy and/or hyperplasia of the bronchial wall muscle with increased extracellular matrixLets learn Pathology Conceptually - Subscribe here today - Better late than never. If you have been lethargic waiting for the push to make your schedule streamlined -  Be a part of #pathocubs

Robbins Review Vignettes

Last question answer - MacrophageA 35-year-old woman takes acetylsalicylic acid (aspirin) for arthritis. Although her joint pain is reduced with this therapy, the inflammatory process continues. The aspirin therapy alleviates her pain mainly through reduction in the synthesis of which of the following mediators? □ (A) Complement C1q □ (B) Prostaglandins□ (C) Leukotriene E4 □ (D) Histamine Revision series -  Scheduled lectures and tests after every lecture - Subscribe here today to give your best for upcoming NEET PG

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