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Identify ?

The previous image was that of Megakaryoblast - Markers -  CD41, CD42, CD61. Let's Relearn Pathology more conceptually ! Let's not memorise, lets understand - Subscribe here today to join #pathocubs The below are myeloblasts seen in a 25 year old diagnosed as AML. Based on the below finding what is the probable mutation seen in the patient? a) CEBPAb) NPM1c) RUNXd) MLL 

Man Kind - A Very Good Morning!

I was just listening to someone yesterday and there was a passing mention by the person, where he said "The uniqueness to humans which is different from other mammals, is we don't have any boundary" We try to go beyond the limitsWe extend our capabilities and still be our own human kindWe tend to break the rules !Isn't so true ? We love to break the rules and we don't like if someone says "This is what you have to do" and if anyone says that we will first do exactly the opposite. Who are you to say attitude?  So this is a negative energy in my opinion, but its a character of all of us, so how are we going to utilise it towards our benefit is what we have to look at. We do not like if someone says you can't do. So I am the negative source here for today, I shall remind it late in the evening as well. Today I am going to put two videos for our revision series - One is on Genetics (the diagnosis part) and the other one is on Immunlogy (Tolerance) in #relearnpatho. And i am sure not even 10% will see both, let's see if you can be in the 10% !!Let's make it a challenge, if you can see both today - you win ! Else your internal negative force is going to win, lets see whom YOU are going to let win !A Very Good Morning !

Identify ?

The last question's answer is DLBCL -  A large mass in spleen.  Let's Relearn Pathology more conceptually ! Let's not memorise, lets understand - Subscribe here today to join #pathocubsQ) Name the CD marker which will be useful for the diagnosis for the blasts as shown below in Bone Marrow? a) CD10, CD20b) CD3c) CD14, CD64d) CD 41, CD42

KRAS Here we come !

 KRAS G12C inhibitor - SotorasibApproved for locally advanced or metastatic non–small cell lung cancer (NSCLC)CodeBreaK 200 - study enrols patients with the above change

Identify !

Yesterday's picture of spleen - Diagnosis - Follicular lymphoma. The white nodules are areas of tumour involving White Pulp of spleen. Lets relearn Pathology - Monday decides the most of the week, take a decision today and join our #pathocubs and regularise your schedule ! Subscribe here today Identify the lesion of spleen shown below? a) CLLb) FollicularC) DLBCLd) CML

Identify ?

Which of the following lymphoma can have the below appearance in SPLEEN?a) DLBCLb) Follicular lymphomac) Hairy cell leukemiad) AMLLet's learn and relearn pathology - Subscribe here today and get access to all scheduled videos in revision.  n

Enough Relaxing !

So i hope your weekend is going smoothly till now. ! Let's learn something new now - Have uploaded a FREE Video on B Cell's Journey -  in the Free Video section.No more memorising CD Markers for B cell Neoplasms ! - Subscribe here today and lets learn the entire pathology conceptually !

Weekend !

We always need rest we are not machines - we need time to take rest so that we can come back more stronger. So tomorrow make it happen. I know some of you might be reading through out, some of you must be relaxing daily :P If you have been reading regularly and exhausting yourself - Take some rest tomorrow. Sleep earlyWake up a bit lateWith no stress - go play somethingWatch something on TV without any inhibition of that you are wasting time. So tomorrow till noon -  Its our free time..! And let's make this happen. Before planning just make a short plan of what you are going to do tomorrow morning. Let continue our routine of Genetics Tomorrow night again !  I shall upload on time 8 pm ! Subscribe here today and join us :) 

Next week Schedule

We are slowly crawling into the successful third schedule of revision and we shall beat out the procrastination. !! You must have written the test on Chapter 2 already -  There were a few questions which were tricky and i hope the explanations might have helped. !Schedule:December 12 - Mendelian InheritanceDecember 13 -  Non Mendelian & Lyon HypothesisDecember 14 - Chromosomal disordersDecember 15 - Genetic diagnosisDecember 16 - Test on Genetics + Mechanisms of Autoimmunty December 17 - SLE and SjogrensDecember 18 - Primary ImmunodeficiencyDecember 19 - Graft RejectionDecember 20 - IgG4 + Amyloidosis Lets stick to this and lets relearn Pathology with fun - Subscribe here today to join our #pathocub community

Identify ?

Something easy to start with . This is from a bone marrow biopsy of a 12 year old kid with failure to thrive and hepatosplenomegaly.. !This can be asked as a spotter as well. Name the finding seen in the marked macrophage ! Lets "Relearn" pathology - Subscribe here today to get access to revision course ?