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Robbins Review Vignettes

A 55-year-old previously healthy man has had episodes of pain and swelling of the right first metatarsophalangeal (MP) joint for the past year. These flare-ups usually occur after consumption of alcohol, typically port wine (six grapes). On physical examination, there is exquisite tenderness with swelling and erythema of the right first MP joint. A joint aspiration is performed, and laboratory studies of the fluid obtained show needle-shaped crystals and many neutrophils in a small amount of fluid. Which of the following laboratory findings is most likely to be reported in this man? Increased serum parathyroid hormone levelElevated serum urea nitrogen levelHyperuricemiaMarkedly elevated levels of serum transaminasesEnroll to Pathology revision series and attend the Live TnD this sunday - Subscribe here today

Robbins Review Vignettes

A 49-year-old woman has been bothered for at least 20 years by recurring skin lesions that are most prominent over the elbows and knees and also sometimes on the scalp and lumbosacral area. These skin lesions are silvery to salmon-colored 1- to 4-cm plaques with scaling. The lesions seem to form more readily at sites of minor trauma, such as a superficial abrasion. She has had increasing pain in her left hand and in her hips, more prominent on the left, over the past 2 years. On physical examination, she has yellow-brown discoloration with pitting of the fingernails. The distal interphalangeal joints of digits two and three of the left hand are slightly swollen and tender. There is minimal reduction in left hip mobility and no swelling or warmth to the touch. A radiograph of the left hip shows minimal joint space narrowing and surface erosion. Bone density is not markedly reduced. During the next 10 years, the joint pain persists, but there is no joint destruction or deformity. She continues to have the same skin lesions. Which of the following is most likely to be seen on biopsy of these skin lesions? Bandlike upper dermal infiltrate of lymphocytesEpidermal spongiosis with dermal edema and eosinophilsFocal keratinocyte apoptosisHyperkeratosis with parakeratosis and elongated rete ridgesHemat TnD will be live tomorrow  - Get access to all Tnd - Enrol to Pathology Revision course - Subscribe here today

Robbins Review Vignettes

A 50-year-old woman has been bothered by a discolored area of skin on her forehead that has not faded during the past 3 years. On physical examination, there is a 0.8-cm red, rough-surfaced lesion on the right forehead above the eyebrow. A biopsy specimen examined microscopically shows hyperkeratosis and thinning of the epidermis with atypical basal cells. The upper dermal collagen and elastic fibers show homogenization with elastosis. Which of the following is the most appropriate advice to give this patient? Reduce intake of dietary fatWear a hat outdoorsStop taking aspirin for headachesApply hydrocortisone cream to your faceGet all the answer and explanation - Week 5 live discussion of tests for registered users  -  Pathology Revision Series - Subscribe here today

No more underdogs

Have you ever noticed that most of the movie which features underdogs is a success ? Like even in IPL most of us become happy when an underdogs performs well when compared to an established player ?Do you ever think why ? The reason is simple - we relate to them so easily. It's deeep in our brains that we are tuned to think we are underdogs by various external factors for various gains -  that's the reason whenever you feel an underdog win you almost consider that as your victory. Same things happened with the movie Slum dog millionaire or Lagaan or the Monsters Inc or any movie you remember. My personal opinion is that this thought process should change, you are not an underdogs and there is no victory by luck. Change your attitude. !There is only one things which gives you success and that is tireless hardwork towards a goal. And don't ever consider that you are underdog, you are a #pathocub and you are born to win with your hardwork, and the only ladyluck you possess is your mother and no one else. You struggle, you burn the midnight oil, you win. Period. ! And you will win no second thoughts :) A very good morning !

Add to your notes

Chorionic villus sampling This technique, typically performed at 10–12 weeks’ gestation, involves the removal of a small sample of chorionic villus material (either a transcervical or a transabdominal approach may be used). The villi are of fetal origin and thus provide a large sample of actively dividing fetal cells for diagnosis. This technique has the advantage of providing a diagnosis earlier in the pregnancy. There is a small possibility of diagnostic error because of placental mosaicism (i.e., multiple cell types in the villi). The risk of fetal demise is higher than with amniocentesis (about 1/100). Get to know the recent advances and practical application in Pathology - Must need for NEET  - Enrol to Pathology revision series - Subscribe here today

A gift to all students

Dear Students,I am trying to collect all the high yield points under a folder. Have started it  - shall segregate it chapter wise - so it's easy for you guys for later reading. You will see them in learn section -  High Yield Pathology Pearls. It will be available for all students in the mobile app.  I shall add notes to them from time to time. !Keep reading and Keep spreading the knowledge :) Best wishes. Get access to entire Pathology Live classes from Nov 5  - Subscribe here today

Instinct

In your exams - You will come across times when you will have to diagnose a difficult condition, which will be confusing. But even in that time - You will have a spinal thought about a diagnosis, which you cannot answer why, but still you will have the instinct that yes it's the diagnosis. Go ahead with it.  It's not a guess, it's your natural response to any complex situation with the data you mind knows, it's a gift to all mammals. Instinct is inborn and is hardly goes wrong !! Believe in yourself. And remember instinct is so powerful, use it in every aspect of your life - If you feel like doing it do it ! (like for example comment on this post - good morning). It made you smile isn't that's the whole motive :) A very good morning. 

Robbins Review Vignettes

A 45-year-old previously healthy man has developed headaches over the past month. On physical examination, there are no remarkable findings. A cerebral angiogram shows a 7-mm saccular aneurysm at the trifurcation of the right middle cerebral artery. Which of the following is most likely to result from this lesion? Epidural hematomaSubarachnoid hemorrhageSubdural hematomaCerebellar tonsillar herniationAnswer and Explanation will be updated in Pathology Revision course - Enrol today and get validity till MAY INI - Subscribe here today

How to access the tests !?

Dear students,Since there are quite a few students asking their queries via student representatives. Just a out look of the app.Free tests will be open by 9pm you will get a notificationFor iOS users  - the free tests will be in Recall Questions Free  --> Free contentFor Android users  - You can access them from the main screenTo access the entire Pathology Revision programme  -  Subscribe here today. Interested in becoming a student representative -  Connect with our Team here

Robbins Review Vignettes

A 30-year-old man comes to his physician because he has noticed increasing enlargement and a feeling of heaviness in his scrotum for the past year. On physical examination, the right testis is twice its normal size, and it is firm and slightly tender. An ultrasound examination shows a 3.5-cm solid mass in the right testis. An abdominal CT scan shows enlargement of the para-aortic lymph nodes. Multiple lung nodules are seen on a chest radiograph. Laboratory findings include markedly increased serum levels of chorionic gonadotropin and α-fetoprotein. Which of the following testicular neoplasms is the most likely diagnosis? Leydig cell tumorMixed germ cell tumorPure spermatocytic seminomaChoriocarcinomaAnswer and Explanation will be updated in Pathology Revision course - Enrol today and get validity till MAY INI - 500+ clinical vignettes, Video solution for all, Recalls and Image Bank - Subscribe here today

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